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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNK2
All Species:
27.58
Human Site:
S455
Identified Species:
60.67
UniProt:
Q07912
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07912
NP_001010938.1
1038
114569
S455
G
L
S
A
Q
D
I
S
Q
P
L
Q
N
S
F
Chimpanzee
Pan troglodytes
XP_001170078
532
57840
D39
V
T
R
P
E
H
F
D
F
V
K
P
E
D
L
Rhesus Macaque
Macaca mulatta
XP_001101686
1038
114517
S455
G
L
S
A
Q
D
I
S
Q
P
L
Q
N
S
F
Dog
Lupus familis
XP_545148
1041
114947
S455
G
L
S
A
Q
D
I
S
Q
P
L
Q
N
S
F
Cat
Felis silvestris
Mouse
Mus musculus
O54967
1055
116957
S455
G
L
S
A
Q
D
I
S
Q
P
L
Q
N
S
F
Rat
Rattus norvegicus
Q5U2X5
1040
115050
S455
G
L
S
A
Q
D
I
S
Q
P
L
Q
N
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517377
665
71250
R172
D
P
L
G
A
G
L
R
R
L
C
L
R
K
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919038
1007
113912
S407
G
L
S
A
H
D
I
S
R
P
L
K
N
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7F7
1337
147458
D468
G
L
P
S
S
T
R
D
S
F
S
R
V
S
D
Honey Bee
Apis mellifera
XP_396503
1302
145297
S439
R
K
Q
P
E
D
I
S
K
P
L
E
N
S
F
Nematode Worm
Caenorhab. elegans
Q10925
1237
134472
S477
N
D
R
T
S
K
I
S
M
P
V
A
G
S
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.4
98.5
94.3
N.A.
92.8
93.7
N.A.
38.3
N.A.
N.A.
56.1
N.A.
25.1
32.4
27.1
N.A.
Protein Similarity:
100
34.4
98.8
95.7
N.A.
94.2
95.5
N.A.
45.8
N.A.
N.A.
67.2
N.A.
40.6
47.3
41.3
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
N.A.
N.A.
80
N.A.
20
53.3
33.3
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
93.3
N.A.
33.3
73.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
55
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
10
0
0
0
64
0
19
0
0
0
0
0
10
10
% D
% Glu:
0
0
0
0
19
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
73
% F
% Gly:
64
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
10
0
10
10
0
10
0
% K
% Leu:
0
64
10
0
0
0
10
0
0
10
64
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% N
% Pro:
0
10
10
19
0
0
0
0
0
73
0
10
0
0
10
% P
% Gln:
0
0
10
0
46
0
0
0
46
0
0
46
0
0
0
% Q
% Arg:
10
0
19
0
0
0
10
10
19
0
0
10
10
0
0
% R
% Ser:
0
0
55
10
19
0
0
73
10
0
10
0
0
82
0
% S
% Thr:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
10
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _